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KMID : 0371319610030050017
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Journal of the Korean Surgical Society
1961 Volume.3 No. 5 p.17 ~ p.21
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Hypotermia : 2. Antifibrillatory Action of Pronestyl (Procaine Amide) upon Ventricular Fibrillation in the the Hypothermic Dog
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이성행/Lee SH
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Abstract
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A study was carried cut to determine the effect of Pronestyl upon ventricular fibrillation occurring hypothermia. Hypothermia was induced in 23 dogs including 8 controls by body surface cooling with ice water and rewarming with hot water(45-48?).
Following induction of hypothermia, Pronestyl was given intravenously in doses of 5mg, 10 mg and 20mg per kg of body weight. Thereafter, cardiac inflow and outflow tracts were occluded for 10 minutes at an esophageal temperature of 22?1?, during which time atriotomy was performed. No notable decrease in ventricular fibrillation attributable to Pronestyl was noted.
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KEYWORD
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